Hemoglobinopathies Market is Anticipated to Boost the Growth at USD 15.7 billion over the Forecast Period

 Hemoglobinopathie Industry Overview

The global hemoglobinopathies market size was valued at USD 7.1 billion in 2020 and is expected to expand at a compound annual growth rate (CAGR) of 10.8% from 2021 to 2028.

The rising prevalence of conditions such as sickle cell disease (SCD) and thalassemia, coupled with the presence of a strong product pipeline for the treatment of hemoglobinopathies, is expected to fuel the market growth. It is estimated that thalassemia affects around 4.4 per 10,000 live births globally. Moreover, around 40 million thalassemia carriers are present in India. Furthermore, according to the WHO, over 330,000 babies are born with hemoglobin disorders each year. Major factors leading to the high prevalence of hemoglobinopathies include lack of awareness, unmet needs related to the treatment of sickle cell disease and thalassemia, and lack of a permanent cure.

Gather more insights about the market drivers, restrains and growth of the Global Hemoglobinopathies Market

Increasing prevalence of hemoglobinopathies in developing and low-income countries is anticipated to boost the market growth over the forecast period. According to a report published by the American Society of Hematology, more than 95% of children born with thalassemia in the world are from low- and middle-income countries, and less than 5% of children born with thalassemia live in North America and the European region. Lack of awareness and high unmet needs related to the diagnosis and treatment are some of the major factors increasing the prevalence in low-income countries. According to the CDC, the incidence of sickle cell disease trait in the U.S. was found to be 15.5 cases per 1,000 births. In addition, 1.5% of babies born in the U.S. have sickle cell trait.

The incidence of hemoglobinopathies depends upon geography, race, ethnicity, and migration. Moreover, the incidence of hemoglobin related diseases is higher in the Mediterranean area and sub-Saharan Africa and Asia region. The migration from high prevalence regions has substantially increased the number of new cases of hemoglobinopathies in North America and the European region. For instance, according to the CDC, there are around 100,000 Americans with sickle cell disease living in the country. In the U.S., sickle cell disease occurs in one out of every 365 African-American births, whereas in Hispanic-American, the incidence of SCD is 1 out of every 16,300 births. Around 1 in 13 African-American newborns has sickle cell trait.

Rising investment in the development of novel therapies is expected to provide impetus to market growth in the coming years. Major biopharmaceutical players are collaborating to develop novel therapeutics for hemoglobinopathies using the latest technology platforms. For instance, Sangamo Therapeutics, Inc. and Bioverativ have collaborated to develop therapeutics for hemoglobinopathies. Moreover, increasing approvals from the regulatory bodies for novel therapies are expected to boost the market growth. For instance, in 2019, the FDA approved Reblozyl, Adakveo, Zynteglo, and Oxbryta for the treatment of hemoglobin disorders. Moreover, various programs undertaken by governments such as thalassemia screening in neonates and providing medicines are expected to impact the market growth positively. Increasing awareness about hemoglobin disorders may lead to an increase in the demand for prevention, diagnosis, and treatment methods.

Browse through Grand View Research's Pharmaceuticals Industry Research Reports

• Medical Foods Market: The global medical foods market size was valued at USD 21.2 billion in 2021 and is expected to expand at a compound annual growth rate (CAGR) of 5.2% from 2022 to 2030.
• Cannabis Pharmaceuticals Market: The global cannabis pharmaceuticals market size was valued at USD 943.5 million in 2021 and is expected to expand at a compound annual growth rate (CAGR) of 104.2% from 2022 to 2028. 

Hemoglobinopathies Market Segmentation

Grand View Research has segmented the global hemoglobinopathies market on the basis of type, diagnosis, therapy, and region:

• Hemoglobinopathies Type Outlook (Revenue, USD Million, 2017 - 2028)
  • Thalassemia
  • Sickle Cell Disease
  • Other Hemoglobin (Hb) Variants
• Hemoglobinopathies Diagnosis Outlook (Revenue, USD Million, 2017 - 2028)
  • Thalassemia
    • Blood Test
    • Genetic Test
    • Prenatal Genetic Test
    • Pre-implantation Genetic Diagnosis
    • Electrophoresis
    • Others
  • Sickle Cell Disease
    • Blood Test
    • Genetic Test
    • Prenatal Genetic Test
    • Electrophoresis
    • Others
  • Other Hemoglobin (Hb) Variants
    • Blood Test
    • Genetic Test
    • Prenatal Genetic Test
    • Electrophoresis
    • Others
  • Hemoglobinopathies Therapy Outlook (Revenue, USD Million, 2017 - 2028)
    • Thalassemia
      • Blood Transfusion
      • Iron Chelation Therapy
      • Bone Marrow Transplant
      • Others
    • Sickle Cell Disease
      • Blood Transfusion
      • Hydroxyurea
      • Bone Marrow Transplant
      • Others
    • Other Hemoglobin (Hb) Variants
      • Blood Transfusion
      • Hydroxyurea
      • Iron Chelation Therapy
      • Bone Marrow Transplant
      • Others
    • Hemoglobinopathies Regional Outlook (Revenue, USD Million, 2017 - 2028)
    • North America
    • Europe
    • Asia Pacific
    • Central & South America
    • Middle East & Africa (MEA)

Market Share Insights

• December 2017: CRISPR Therapeutics AG and Vertex Pharmaceuticals Incorporated entered into a partnership to develop and commercialize novel gene-editing treatments for thalassemia using CRISPR/Cas9 technology.

Key Companies profiled:

Market players are taking up various initiatives, such as mergers & acquisitions, partnerships, collaborations, and extensive R&D, in order to gain a greater share in the market.

 Some prominent players in the global hemoglobinopathies market include:

• Sangamo Therapeutics, Inc.
• Global Blood Therapeutics, Inc.
• bluebird bio, Inc.
• Emmaus Life Sciences Inc.
• Pfizer, Inc.
• Novartis AG
• Prolong Pharmaceuticals, LLC
• Bioverativ Inc.
• Gamida Cell

Order a free sample PDF of the Hemoglobinopathies Market Intelligence Study, published by Grand View Research.

About Grand View Research

Grand View Research, U.S.-based market research and consulting company, provides syndicated as well as customized research reports and consulting services. Registered in California and headquartered in San Francisco, the company comprises over 425 analysts and consultants, adding more than 1200 market research reports to its vast database each year. These reports offer in-depth analysis on 46 industries across 25 major countries worldwide. With the help of an interactive market intelligence platform, Grand View Research Helps Fortune 500 companies and renowned academic institutes understand the global and regional business environment and gauge the opportunities that lie ahead.